Korkushko O V, Fedirko M I, Gidzinskaia I N
Vrach Delo. 1990 Feb(2):10-3.
It was established that monotherapy with captopril was effective in 72% of patients with hypertensive disease in the elderly. Reduction of the arterial pressure is accompanied by an improvement of the indices of hemodynamics and myocardial contractility as well as relaxation of the left ventricle. Captopril proved more effective in patients with a high concentration of blood angiotensin. Acute load by a single intake of 25 mg of captopril may with high probability predict the efficacy of treatment courses, namely, in patients with a good clinical efficacy reduction of the preparation. Captopril is recommended for the treatment of hypertensive disease in the elderly.
已证实,卡托普利单药治疗对72%的老年高血压病患者有效。动脉压降低伴随着血流动力学指标、心肌收缩力改善以及左心室舒张。卡托普利在血中血管紧张素浓度高的患者中疗效更佳。单次服用25毫克卡托普利产生的急性负荷很可能预示治疗疗程的疗效,即在临床疗效良好的患者中该制剂可降低血压。推荐使用卡托普利治疗老年高血压病。