Van Houtte P, Roelandts M, Mornex F
Département de radiothérapie-oncologie, institut Jules-Bordet, Bruxelles, Belgique.
Cancer Radiother. 2011 Oct;15(6-7):509-13. doi: 10.1016/j.canrad.2011.07.228. Epub 2011 Aug 27.
Traditionally, the target volumes of curative-intent radiotherapy for non-small cell lung cancer include all uninvolved mediastinal nodes. However, an improvement in tumour control requires an increase of the total dose to the macroscopic target volume. This is only achievable if the irradiation of the organs at risk is reduced, i.e. elective irradiation of the mediastinum is omitted. The available data suggest that elective mediastinal irradiation may be safely omitted, provided that an adequate staging procedure, including FDG PET-CT, has been performed.
