King Fahad Cardiac Center, King Khalid University Hospital, College of Medicine, King Saud University, PO Box 7805, Riyadh 11472, Kingdom of Saudi Arabia.
Eur J Heart Fail. 2011 Nov;13(11):1178-84. doi: 10.1093/eurjhf/hfr111. Epub 2011 Aug 25.
The heart function assessment registry trial in Saudi Arabia (HEARTS) is the first multicentre national quality improvement initiative in the Arab population to study the clinical features, management, and outcomes of inpatients admitted with acute heart failure (AHF) and outpatients with high-risk chronic heart failure (HCHF).
We conducted a prospective pilot phase for the registry that included consecutive patients with AHF and HCHF in five tertiary care hospitals in Saudi Arabia between October 2009 and December 2010. The study enrolled 1090 patients, 722 (66.2%) of whom were admitted with AHF and 368 (33.8%) had HCHF. The mean age ± SD of AHF patients was 60.6 ± 15.3 years; 65.2% were men, 55.3% were de novo heart failure, 60.7% had diabetes mellitus, 72.5% had moderate or severe left ventricular (LV) systolic dysfunction, and 51.5% had coronary artery disease as the main aetiology. More than 80% of AHF and HCHF patients were treated with beta-blockers and angiotensin-converting enzyme inhibitors/angiotensin receptor blockers. Patients with HCHF had a similar clinical profile, but only one-third had implantable cardioverter defibrillators. In-hospital mortality was 5.3% for AHF patients and 7.5% at 30 days after hospital discharge.
Heart failure patients in Saudi Arabia present at a relatively younger age, have a much higher rate of diabetes mellitus, and predominantly have LV systolic dysfunction, which is mainly ischaemic in origin, compared with patients in developed countries. The preliminary results of the study show potential targets for improvement in care.
沙特阿拉伯心脏功能评估登记研究（HEARTS）是阿拉伯人群中首个多中心国家质量改进计划，旨在研究急性心力衰竭（AHF）住院患者和高危慢性心力衰竭（HCHF）门诊患者的临床特征、管理和结局。
我们对该登记进行了前瞻性试点阶段，纳入了 2009 年 10 月至 2010 年 12 月期间沙特阿拉伯五家三级保健医院的连续 AHF 和 HCHF 患者。该研究共纳入 1090 例患者，其中 722 例（66.2%）因 AHF 住院，368 例（33.8%）患有 HCHF。AHF 患者的平均年龄±标准差为 60.6±15.3 岁；65.2%为男性，55.3%为新发心力衰竭，60.7%患有糖尿病，72.5%有中度或重度左心室（LV）收缩功能障碍，51.5%的主要病因是冠状动脉疾病。超过 80%的 AHF 和 HCHF 患者接受了β受体阻滞剂和血管紧张素转换酶抑制剂/血管紧张素受体阻滞剂治疗。HCHF 患者具有相似的临床特征，但只有三分之一的患者植入了心脏复律除颤器。AHF 患者的住院死亡率为 5.3%，出院后 30 天的死亡率为 7.5%。
与发达国家的患者相比，沙特阿拉伯心力衰竭患者就诊时年龄相对较轻，糖尿病患病率更高，LV 收缩功能障碍更为常见，且主要源于缺血性病因。该研究的初步结果显示出改善治疗的潜在目标。
