Al-Balbissi Kais, Al-Saleh Akram, Al-Makhamreh Hanna, Abu-Hantash Hadi, Toubasi Ahmad, Albustanji Farah, Obaid Yazan Y, Abu Tawileh Hind, Al-Qalalweh Sarah, Mahmoud Mohammad Y, Hobeika Louis, Awaisheh Toqa, Izraiq Mahmoud
Cardiology Section, Internal Medicine Department, Jordan University Hospital, Amman, Jordan.
Department of Cardiology, Amman Surgical Hospital, Amman, Jordan.
Ann Med Surg (Lond). 2025 Apr 4;87(5):2659-2667. doi: 10.1097/MS9.0000000000003255. eCollection 2025 May.
Heart failure is one of the most common medical burdens facing the healthcare system worldwide. Based on our knowledge, only two heart failure registries have been conducted in the Middle East. Therefore, we decided to conduct this heart failure registry to investigate the follow-up results of patients with both acute and chronic heart failure in Jordan.
This study is a prospective observational multicenter national registry encompassing 21 health institutes in Jordan, comprising university hospitals, private hospitals, and private clinics. The criteria of inclusion were patients visiting the cardiology clinic or inpatients who were admitted due to acute decompensated HF. The primary outcome was 30-day mortality.
The total number of enrolled patients in the study was 2128, with a total number of deaths during the follow-up of 204. Multivariate analysis demonstrated that smoking (odds ratio [OR] = 3.214; 1.005-5139), positive family history of premature coronary artery disease (OR = 2.686; 1.504-4.798), insulin (OR = 2.300; 1.356-3.899), hyponatremia at presentation (OR = 7.058; 1.698-29.342) and increased left ventricular diameter (OR = 1.009; 1.002-1.016) were significantly associated with higher odds of mortality.
Smoking, positive family history of premature coronary artery disease, insulin use, hyponatremia on presentation, and increased left ventricular diameter were associated with patients' mortality. Physicians should monitor these factors among patients to identify patients who are at higher risk of detrimental outcomes.
心力衰竭是全球医疗系统面临的最常见医疗负担之一。据我们所知，中东地区仅开展过两项心力衰竭登记研究。因此，我们决定开展这项心力衰竭登记研究，以调查约旦急性和慢性心力衰竭患者的随访结果。
本研究是一项前瞻性观察性多中心全国登记研究，涵盖约旦的21家医疗机构，包括大学医院、私立医院和私人诊所。纳入标准为就诊于心脏病诊所的患者或因急性失代偿性心力衰竭入院的住院患者。主要结局为30天死亡率。
该研究共纳入2128例患者，随访期间共有204例死亡。多因素分析表明，吸烟（比值比[OR]=3.214；1.005 - 5.139）、早发冠状动脉疾病家族史阳性（OR = 2.686；1.504 - 4.798）、胰岛素使用（OR = 2.300；1.356 - 3.899）、就诊时低钠血症（OR = 7.058；1.698 - 29.342）和左心室直径增大（OR = 1.009；1.002 - 1.016）与较高的死亡几率显著相关。
吸烟、早发冠状动脉疾病家族史阳性、胰岛素使用、就诊时低钠血症和左心室直径增大与患者死亡率相关。医生应在患者中监测这些因素，以识别出不良结局风险较高的患者。
