Drouet M, Le Sellin J, Bonneau J C, Sabbah A
Laboratoire d'Immuno-Allergologie, CHRU, Angers.
Allerg Immunol (Paris). 1990 Mar;22(3):81, 84-8.
Mercury is a well-known allergen in dermato-allergology, often manifesting as delayed type hypersensitivity contact eczema. Immediate hypersensitivity reactions (urticaria, anaphylactic shock) have also been described for this allergen, most frequently seen in patients with the delayed type contact eczema. To our knowledge this allergen has not been implicated in production of respiratory symptoms. We describe a patient who had aggravation of asthma by mercury contained in dental amalgam. When the dental amalgam was removed there was a great improvement in his asthma. This observation suggests that mercury in the form of dental amalgam may also be an allergen of the respiratory tract, which should not be surprising, bearing in mind the work that shows the existence of mercury vapours from dental amalgam.
汞是皮肤过敏学中一种广为人知的变应原，常表现为迟发型超敏反应性接触性湿疹。针对这种变应原也有速发型超敏反应（荨麻疹、过敏性休克）的相关描述，最常见于患有迟发型接触性湿疹的患者。据我们所知，这种变应原与呼吸道症状的产生并无关联。我们描述了一名患者，其因牙科汞合金中的汞而导致哮喘加重。当去除牙科汞合金后，他的哮喘有了很大改善。这一观察结果表明，牙科汞合金形式的汞也可能是呼吸道的一种变应原，考虑到有研究表明牙科汞合金会释放汞蒸气，这并不令人惊讶。
