Cikes Nada
Zavod za klinikku imunologiju i reumatologiju, Kispatićeva 12,10000 Zagreb.
Reumatizam. 2010;57(2):99-104.
In patients with systemic sclerosis heart involvement is often manifest, associated with poor prognosis and increased mortality. Cardiac involvement may be manifested by myocardial disease, arrhhythmias, conduction system disturbances, pericardial abnormalities and right heart failure, which develops as a complication of pulmonary arterial hypertension and significantly influences the disease progression. Pulmonary arterial hypertension is a severe and progressive disease with significant morbidity and mortality, being more often diagnosed. Diagnostic methods in evaluation of heart involvement as well as pulmonary arterial hypertension are presented. Today's treatment modalities are discussed.
在系统性硬化症患者中，心脏受累常常很明显，与预后不良和死亡率增加相关。心脏受累可能表现为心肌病、心律失常、传导系统紊乱、心包异常以及右心衰竭，后者是肺动脉高压的并发症，会显著影响疾病进展。肺动脉高压是一种严重的进行性疾病，发病率和死亡率都很高，且越来越常被诊断出来。本文介绍了评估心脏受累以及肺动脉高压的诊断方法，并讨论了当今的治疗方式。
