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The heat shock response of Mycobacterium tuberculosis: linking gene expression, immunology and pathogenesis.
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Functional analysis of GlnE, an essential adenylyl transferase in Mycobacterium tuberculosis.
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Protection elicited by two glutamine auxotrophs of Mycobacterium tuberculosis and in vivo growth phenotypes of the four unique glutamine synthetase mutants in a murine model.
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All four Mycobacterium tuberculosis glnA genes encode glutamine synthetase activities but only GlnA1 is abundantly expressed and essential for bacterial homeostasis.
Mol Microbiol. 2005 Nov;58(4):1157-72. doi: 10.1111/j.1365-2958.2005.04899.x.
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The use of microarray analysis to determine the gene expression profiles of Mycobacterium tuberculosis in response to anti-bacterial compounds.
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Dissection of the heat-shock response in Mycobacterium tuberculosis using mutants and microarrays.
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glnE is an essential gene in Mycobacterium tuberculosis.
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An inhibitor of exported Mycobacterium tuberculosis glutamine synthetase selectively blocks the growth of pathogenic mycobacteria in axenic culture and in human monocytes: extracellular proteins as potential novel drug targets.
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Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
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