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创伤后颅骨囊性纤维发育不良

Posttraumatic cranial cystic fibrous dysplasia.

作者信息

Tomiyama Arata, Aoki Kazuya, Nakayama Haruo, Izukura Hideaki, Kimura Hitoshi, Harashina Jun-Ichi, Ito Keisuke, Hayashi Morito, Saito Norihiko, Sakurai Takatoshi, Oharaseki Toshiaki, Terada Hitoshi, Iwabuchi Satoshi

机构信息

Division of Metastasis and Invasion Signaling, National Cancer Center, Research Institute, Tokyo 104-0045, Japan.

出版信息

Case Rep Med. 2011;2011:680401. doi: 10.1155/2011/680401. Epub 2011 Aug 25.

Abstract

A 14-year-old was girl admitted to our hospital with a subcutaneous mass of the occipital head. The mass had grown for 6 years, after she had sustained a head injury at the age of 6, and was located directly under a previous wound. Skull X-ray Photograph (xp), computed tomography (CT), and magnetic resonance imaging (MRI) showed a bony defect and cystic changes in the skull corresponding to a subcutaneous mass. Bone scintigraphy revealed partial accumulation. The patient underwent total removal of the skull mass, and the diagnosis from the pathological findings of the cyst wall was fibrous dysplasia (FD). The radiographic findings for cystic cranial FD can be various. Progressive skull disease has been reported to be associated with head trauma, but the relationship between cranial FD and head trauma has not been previously reported. Previous studies have suggested that c-fos gene expression is a key mechanism in injury-induced FD.

摘要

一名14岁女孩因枕部皮下肿物入院。该肿物在她6岁头部受伤后已生长6年,位于先前伤口的正下方。颅骨X线照片(XP)、计算机断层扫描(CT)和磁共振成像(MRI)显示颅骨有骨缺损和囊性改变,与皮下肿物相对应。骨闪烁显像显示有部分放射性聚集。患者接受了颅骨肿物全切术,根据囊肿壁的病理检查结果诊断为纤维性骨发育不良(FD)。囊性颅骨FD的影像学表现可能多种多样。据报道,进行性颅骨疾病与头部创伤有关,但颅骨FD与头部创伤之间的关系此前尚未见报道。先前的研究表明,c-fos基因表达是损伤诱导FD的关键机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad80/3162981/7b72d708a39d/CRIM2011-680401.001.jpg

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