Department of Biological Sciences, Federal University of Technology, Minna, Nigeria.
J Trop Med. 2012;2012:274142. doi: 10.1155/2012/274142. Epub 2011 Aug 14.
The study was designed to determine the true prevalence of congenital, cord, and placental malaria in General Hospital Minna, North Central Nigeria. Peripheral blood smears of near-term pregnant women, as well as the placental, cord, and peripheral blood smears of their newborn babies, were examined for malaria parasites, using the Giemsa staining technique. Out of 152 pregnant women screened, 21 (13.82%) of them were infected with malaria parasites. Of the 152 new born babies, 4 (2.63%) showed positive peripheral parasitaemia. Placental parasitaemia was 7/152 (4.61%), while cord blood parasitaemia was 9/152 (5.92%). There were strong associations between peripheral and cord malaria parasitaemia and congenital malaria (P < 0.05). Plasmodium falciparum occurred in all, and none had mixed infection. The average birth weights of the babies delivered of nonmalarious pregnant women were higher than those delivered by malarious pregnant women, though not significant (P > 0.05). Malaria parasitaemia occurred more frequently in primigravidae than multigravidae.
本研究旨在确定尼日利亚中北部明纳综合医院先天性、脐带和胎盘疟疾的真实流行率。使用吉姆萨染色技术,对接近分娩的孕妇的外周血涂片,以及她们新生儿的胎盘、脐带和外周血涂片进行疟原虫检查。在筛查的 152 名孕妇中,有 21 名(13.82%)感染了疟原虫。在 152 名新生儿中,有 4 名(2.63%)出现外周血疟原虫阳性。胎盘疟原虫感染率为 7/152(4.61%),脐带血疟原虫感染率为 9/152(5.92%)。外周血和脐带血疟原虫感染与先天性疟疾之间存在很强的关联(P < 0.05)。所有病例均为恶性疟原虫感染,无混合感染。非疟疾孕妇所分娩婴儿的平均出生体重高于疟疾孕妇所分娩婴儿,但无统计学意义(P > 0.05)。初产妇的疟原虫感染发生率高于多产妇。