利用免疫系统的武器库：生产用于治疗的人源单克隆抗体并研究免疫反应。
Harnessing the immune system's arsenal: producing human monoclonal antibodies for therapeutics and investigating immune responses.
作者信息
Sullivan Meghan, Kaur Kaval, Pauli Noel, Wilson Patrick C
出版信息
F1000 Biol Rep. 2011;3:17. doi: 10.3410/B3-17. Epub 2011 Aug 1.
Abstract
Monoclonal antibody technology has undergone rapid and innovative reinvention over the last 30 years. Application of these technologies to human samples revealed valuable therapeutic and experimental insights. These technologies, each with their own benefits and flaws, have proven indispensable for immunological research and in our fight to provide new treatments and improved vaccines for infectious disease.
摘要
在过去30年里，单克隆抗体技术经历了快速且创新的重塑。将这些技术应用于人类样本揭示了有价值的治疗和实验见解。这些技术各有优缺点，已被证明对于免疫学研究以及我们为传染病提供新治疗方法和改进疫苗的斗争而言不可或缺。
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