Milandre L, Pellissier J F, Vincentelli F, Khalil R
Clinique Neurologique, CHU Timone, Marseille, France.
Eur Neurol. 1990;30(2):93-7. doi: 10.1159/000117319.
Two fatal cases of deep cerebral venous system thrombosis are reported in adults. The first case looked like a diencephalic tumor or encephalitis but the diagnosis was made antemortem by means of cerebral angiography. Autopsy found bilateral infarction of basal ganglia. The second patient presented with a hemorrhagic infarction of right thalamus and basal ganglia. Deep cerebral venous occlusion was diagnosed at autopsy. In spite of a few cases of survival, the thrombosis of the galenic system remains often fatal. The pathological changes and indications for anticoagulation are discussed.
报告了两例成人深部脑静脉系统血栓形成的致命病例。第一例看似间脑肿瘤或脑炎,但生前通过脑血管造影术做出了诊断。尸检发现双侧基底节梗死。第二例患者表现为右侧丘脑和基底节出血性梗死。尸检诊断为深部脑静脉闭塞。尽管有少数存活病例,但大脑大静脉系统血栓形成往往仍会致命。本文讨论了其病理变化及抗凝治疗的指征。