Amorim Bárbara Juarez, Santos Allan de Oliveira, Oberg Telma Dagmar, Romanato Juliana, Anjos Dalton A, Lima Mariana da Cunha Lopes de, Ramos Celso Darío, Honorato Donizete Cesar, Camargo Edwaldo Eduardo, Etchebehere Elba Cristina de Sá Camargo
Serviço de Medicina Nuclear do Departamento de Radiologia, Hospital das Clínicas, UNICAMP, Av. Zeferino Vaz, S/N - Caixa Postal 6149, 13080-000 Campinas SP - Brasil.
Arq Neuropsiquiatr. 2011 Aug;69(4):682-6. doi: 10.1590/s0004-282x2011000500020.
Demonstrate brain perfusion changes due to neuronal activation after functional electrical stimulation (FES).
It was studied 14 patients with hemiplegia who were submitted to a program with FES during fourteen weeks. Brain perfusion SPECT was performed before and after FES therapy. These patients were further separated into 2 groups according to the hemiplegia cause: cranial trauma and major vascular insults. All SPECT images were analyzed using SPM.
There was a significant statistical difference between the two groups related to patient's ages and extent of hypoperfusion in the SPECT. Patients with cranial trauma had a reduction in the hypoperfused area and patients with major vascular insult had an increase in the hypoperfused area after FES therapy.
FES therapy can result in brain perfusion improvement in patients with brain lesions due to cranial trauma but probably not in patients with major vascular insults with large infarct area.
证明功能性电刺激（FES）后神经元激活引起的脑灌注变化。
研究了14例偏瘫患者，他们在14周内接受了FES治疗方案。在FES治疗前后进行脑灌注单光子发射计算机断层扫描（SPECT）。根据偏瘫病因将这些患者进一步分为2组：颅脑外伤和主要血管损伤。所有SPECT图像均使用统计参数映射（SPM）进行分析。
两组在患者年龄和SPECT中灌注不足程度方面存在显著统计学差异。FES治疗后，颅脑外伤患者的灌注不足区域减少，主要血管损伤患者的灌注不足区域增加。
FES治疗可使因颅脑外伤导致脑损伤的患者脑灌注得到改善，但对于大面积梗死区域的主要血管损伤患者可能无效。
