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葡萄牙北部育龄期妇女弓形虫感染的血清流行病学研究。

Seroepidemiology of Toxoplasma gondii infection in women from the North of Portugal in their childbearing years.

机构信息

Department of Veterinary Sciences and Centre for Veterinary and Animal Science, University of Trás-os-Montes e Alto Douro, Vila Real, Portugal.

出版信息

Epidemiol Infect. 2012 May;140(5):872-7. doi: 10.1017/S0950268811001658. Epub 2011 Aug 31.

DOI:10.1017/S0950268811001658
PMID:21878147
Abstract

Seroprevalence of Toxoplasma gondii infection and associated risk factors were investigated in 401 women of childbearing age from the North of Portugal. Of the 98 (24·4%) seropositive women, 92 (93·9%) only had immunoglobulin (Ig)G, two (2·0%) only had IgM, and four (4·1%) others had both IgG and IgM. Risk factors for T. gondii infection in women were: engaging in soil-related activities without gloves [odds ratio (OR) 8·4], consumption of unwashed raw vegetables or fruit (OR 7·6), and consumption of smoked or cured (non-cooked) processed pork products (OR 2·5). Most women of childbearing age from the North Portugal are susceptible to primary infection with T. gondii and, therefore, the risk of congenital toxoplasmosis remains high.

摘要

本研究调查了葡萄牙北部 401 名育龄妇女的弓形虫血清流行率和相关危险因素。在 98 名(24.4%)血清阳性妇女中,92 名(93.9%)仅存在 IgG,2 名(2.0%)仅存在 IgM,4 名(4.1%)其他存在 IgG 和 IgM。妇女感染弓形虫的危险因素为:未戴手套从事与土壤相关的活动(比值比[OR]8.4)、食用未清洗的生蔬菜或水果(OR 7.6)以及食用熏制或腌制(未煮熟)加工猪肉制品(OR 2.5)。葡萄牙北部大多数育龄妇女容易初次感染弓形虫,因此先天性弓形虫病的风险仍然很高。

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