Fuentes Aler, Fresno María Javiera, Santander Hugo, Valenzuela Saúl, Gutiérrez Mario Felipe, Miralles Rodolfo
Departamento de Prótesis, Universidad de Chile, Santiago, Chile.
Rev Med Chil. 2011 Mar;139(3):362-7. Epub 2011 Aug 25.
The five senses have had a fundamental importance for survival and socialization of human beings. From an evolutionary point of view the sense of smell is the oldest. This sense has a strong representation within the genome, allowing the existence of many types of receptors that allow us to capture multiple volatile odor producing molecules, sending electrical signals to higher centers to report the outside world. Several cortical areas are activated in the brain, which are interconnected to form an extensive and complex neural network, linking for example, areas involved with memory and emotions, thus giving this sense of perceptual richness. While the concept of flavor is largely related to the sense of taste, smell provides the necessary integration with the rest of the senses and higher functions. Fully understanding the sense of smell is relevant to health professionals. Knowing the characteristics of the receptors, the transduction processes and convergence of information in the higher centers involved, we can properly detect olfactory disorders in our patients.
五感对于人类的生存和社交具有至关重要的意义。从进化的角度来看,嗅觉是最古老的。这种感觉在基因组中有很强的体现,使得存在多种类型的受体,这些受体能让我们捕捉到多种产生挥发性气味的分子,向更高级中枢发送电信号以汇报外界情况。大脑中的几个皮质区域会被激活,它们相互连接形成一个广泛而复杂的神经网络,例如,将与记忆和情感相关的区域联系起来,从而赋予这种感觉丰富的感知。虽然风味的概念在很大程度上与味觉相关,但嗅觉为与其他感官及更高功能的必要整合提供了支持。全面了解嗅觉对健康专业人员来说很重要。了解受体的特性、转导过程以及在相关更高级中枢中信息的汇聚情况,我们就能在患者中准确检测出嗅觉障碍。