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[自体移植治疗孤立性肾动脉夹层]

[Autotransplantation in the treatment of isolated dissection of the renal artery].

作者信息

Martin X, Salas M, Bouvier R, Bachet P, Dubernard J M

机构信息

Service d'Urologie et Chirurgie de transplantation, Hôpital Edouard-Herriot, Lyon.

出版信息

J Urol (Paris). 1990;96(2):81-5.

PMID:2187932
Abstract

Isolated dissection of renal artery is uncommon; 150 cases were reported in the literature, whose 2/3 diagnosed during patient's life and 1/3 post mortem, during autopsy. From 1976 to 1988 4 cases of isolated dissection of the renal artery were diagnosed and treated in our Institution. Three men and one woman with age ranging from 39 to 46 yrs (mean age 41.75) were seen at our Institution for intense abdominal pain and blood hypertension (mean blood pressure 196.25/113.75 mmHg) of recent occurrence. In 2 cases angiography showed dissection of the left renal artery, with involvement of peripheral branches; in 1 case the dissection involved the right renal artery with complete occlusion of an upper pole branch and upper pole infarction; our youngest patients presented a bilateral dissection, limited to the main trunk on the right side and involving prepelvic and retropelvic branches on the left side. Surgical treatment consisted of renal autotransplantation in the iliac fossa after extracorporeal reconstruction of the arterial pedicule; a branched hypogastric graft was used in 3 patients; in the patient with bilateral dissection an hypogastric graft was used on the right side and a sapehenous graft on the left side (3 months later). Partial nephrectomy was also performed in the patient having right upper pole infarction. Histologic examination showed that dissection always started from lesions of the lamina media. All patient were alive from 6 to 48 months after renal revascularization, with normalization of blood pressure (mean BP 125/80 mmHg); postoperative angiographic control showed thrombosis of 2 small branches in 1 case and partial stenosis of 3 anastomoses in another patient.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

孤立性肾动脉夹层并不常见;文献报道了150例,其中2/3在患者生前诊断,1/3在尸检时诊断。1976年至1988年,我院诊断并治疗了4例孤立性肾动脉夹层。我院收治了3例男性和1例女性患者,年龄在39至46岁之间(平均年龄41.75岁),均因近期出现的剧烈腹痛和高血压(平均血压196.25/113.75 mmHg)前来就诊。2例血管造影显示左肾动脉夹层,累及外周分支;1例夹层累及右肾动脉,上极分支完全闭塞,出现上极梗死;最年轻的患者为双侧夹层,右侧局限于主干,左侧累及盆腔前和盆腔后分支。手术治疗包括在体外重建动脉蒂后将肾脏自体移植至髂窝;3例患者使用了分支的下腹下动脉移植物;双侧夹层患者右侧使用下腹下动脉移植物,左侧使用大隐静脉移植物(3个月后)。右上极梗死患者还进行了部分肾切除术。组织学检查显示,夹层总是从中膜病变开始。所有患者肾血管重建术后存活6至48个月,血压恢复正常(平均血压125/80 mmHg);术后血管造影复查显示,1例患者2个小分支血栓形成,另1例患者3个吻合口部分狭窄。(摘要截断于250字)

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