Su S L, Way L J, Lin R T, Peng M J, Wu S C
Department of Neurology, Kaohsiung Municipal Min Sheng Hospital, Taiwan, Republic of China.
Gaoxiong Yi Xue Ke Xue Za Zhi. 1990 Mar;6(3):155-62.
We report three cases of neuro-Behçet's disease, including one woman and two men (age range 52-56 years), who displayed symptoms of high fever, headache and confusion. The EEG showed generalized slowing in two cases, and periodic lateralized epileptiform discharges in one. Brain CT scans from two patients revealed cortical atrophy with multiple low density areas in one case, and focal contrast enhancement in the other. The CSF study revealed pleocytosis in all cases, but only one showed lymphophagocytosis. All of the patients responded dramatically to steroid therapy, although administration of the drug was somewhat delayed in two cases, during which initial management was aimed at the CNS infection of bacterial origin. Recurrent attacks of confusion or mental dullness were found in two patients, and high cortical dysfunction persisted on follow-up for some time. The clinical manifestations, laboratory findings, and neuroradiological features of neuro-Behçet's disease in the reported cases are reviewed.
我们报告了3例神经白塞病患者，其中包括1名女性和2名男性（年龄范围52 - 56岁），他们均表现出高热、头痛和意识模糊的症状。脑电图显示，2例患者出现广泛性慢波，1例出现周期性局灶性癫痫样放电。2例患者的脑部CT扫描显示，1例出现皮质萎缩并伴有多个低密度区，另1例出现局灶性强化。脑脊液检查显示，所有病例均有细胞增多，但只有1例出现噬淋巴细胞现象。所有患者对类固醇治疗均有显著反应，尽管2例患者用药有所延迟，在此期间初始治疗针对细菌性中枢神经系统感染。2例患者出现反复的意识模糊或精神迟钝发作，随访发现高级皮质功能障碍持续了一段时间。本文对所报告病例中神经白塞病的临床表现、实验室检查结果和神经放射学特征进行了综述。
