Vickers M A, Benson C B, Richie J P
Department of Urology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts 02115.
J Urol. 1990 Jun;143(6):1125-7. doi: 10.1016/s0022-5347(17)40202-3.
Cavernosometry and cavernosography have been the primary modalities available for detection and mapping of corporovenous incompetence in patients with erectile dysfunction. These procedures are expensive, time-consuming and associated with some morbidity, prompting us to study a less invasive method, high resolution ultrasonography and pulsed wave Doppler ultrasound. We evaluated 13 patients with nonendocrinological, nonneurological erectile dysfunction by high resolution and Doppler ultrasound for flow in the dorsal and cavernosal veins after intracorporeal papaverine. All patients had a nonrigid response to papaverine and a mean maximum cavernous arterial systolic velocity of greater than 25 cm. per second. The 13 patients were subsequently studied by dynamic cavernosometry and cavernosography, which revealed evidence of venous incompetence (12 with dorsal venous leaks and 11 with cavernous venous leaks). Only 5 of the 12 patients with dorsal venous incompetence had flow detected in the dorsal vein by ultrasound and Doppler studies. High resolution and Doppler ultrasound was unable to detect leakage in the cavernous veins. Among the 2 groups of patients with dorsal venous leaks (those with and without flow detectable by Doppler ultrasound) there was no significant difference in mean cavernous artery diameter or mean cavernous arterial maximum velocity. Similarly, there was no significant difference between the 2 groups in induction, maintenance or initial decompression rates on cavernosometry. We conclude that high resolution and Doppler ultrasound cannot replace dynamic cavernosometry and cavernosography as the diagnostic modality for venous incompetence.
海绵体测压法和海绵体造影术一直是用于检测和描绘勃起功能障碍患者海绵体静脉功能不全的主要方法。这些检查费用昂贵、耗时且伴有一定的发病率,促使我们研究一种侵入性较小的方法,即高分辨率超声检查和脉冲波多普勒超声检查。我们通过高分辨率和多普勒超声检查,对13例非内分泌、非神经源性勃起功能障碍患者在阴茎海绵体内注射罂粟碱后,评估其背侧和海绵体静脉的血流情况。所有患者对罂粟碱均有非强直反应,且平均最大海绵体动脉收缩期速度大于25厘米/秒。随后对这13例患者进行了动态海绵体测压法和海绵体造影术检查,结果显示存在静脉功能不全的证据(12例有背侧静脉漏,11例有海绵体静脉漏)。在12例有背侧静脉功能不全的患者中,只有5例通过超声和多普勒检查在背侧静脉中检测到血流。高分辨率和多普勒超声检查无法检测到海绵体静脉的渗漏情况。在两组有背侧静脉漏的患者(即多普勒超声可检测到血流和检测不到血流的患者)中,平均海绵体动脉直径或平均海绵体动脉最大速度没有显著差异。同样,在海绵体测压法的诱导、维持或初始减压率方面,两组之间也没有显著差异。我们得出结论,高分辨率和多普勒超声检查不能取代动态海绵体测压法和海绵体造影术作为诊断静脉功能不全的方法。