Iki Masayuki
Department of Public Health, Kinki University Faculty of Medicine, Japan.
Clin Calcium. 2011 Sep;21(9):1377-83.
Burden of osteoporosis in men on our society is increasing with aging in population. Prevalence of osteoporosis and incidence of osteoporotic fracture are less frequent in men than in women since bone mineral density is higher, bone size is greater, and hence the bone is stronger in men than in women. In spite of these facts, the number of male patients with osteoporosis was projected to be 3 million in 2005 and is increasing thereafter. Hip fracture was estimated to occur in 33,100 men in 2007 and is increasing as well. Once a man suffers from hip fracture, prognosis is worse in men than in women. However, screening methods for osteoporosis in men are not established, and this causes delay in diagnosis and treatment. Further studies are necessary to answer whether the current young adult value of bone density necessary for diagnosis is appropriate, whether therapeutic regimens are effective in men, whether the cost for diagnosis and treatment is comparable to benefit, whether a valid screening method for osteoporosis in men exists, and whether the screening method is cost-effective.
随着人口老龄化，男性骨质疏松症给我们社会带来的负担正在增加。由于男性的骨矿物质密度更高、骨骼尺寸更大，因此骨骼比女性更强壮，所以男性骨质疏松症的患病率和骨质疏松性骨折的发生率低于女性。尽管如此，2005年男性骨质疏松症患者人数预计为300万，此后还在增加。2007年估计有33100名男性发生髋部骨折，且这一数字也在上升。男性一旦发生髋部骨折，其预后比女性更差。然而，男性骨质疏松症的筛查方法尚未确立，这导致诊断和治疗延迟。有必要进行进一步研究，以回答目前诊断所需的年轻成年人骨密度值是否合适、治疗方案对男性是否有效、诊断和治疗成本与收益是否相当、是否存在有效的男性骨质疏松症筛查方法以及该筛查方法是否具有成本效益。
