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术前短期强化物理治疗对肺癌患者的影响:一项随机对照试验。

The effects of preoperative short-term intense physical therapy in lung cancer patients: a randomized controlled trial.

作者信息

Pehlivan Esra, Turna Akif, Gurses Atilla, Gurses Hulya Nilgun

机构信息

Chest Diseases and Thoracic Surgery, Yedikule Teaching Hospital, Istanbul, Turkey.

出版信息

Ann Thorac Cardiovasc Surg. 2011;17(5):461-8. doi: 10.5761/atcs.oa.11.01663. Epub 2011 Jul 13.

Abstract

BACKGROUND

We planned to investigate the effect of preoperative short period intensive physical therapy on lung functions, gas-exchange, and capacity of diffusion, and ventilation-perfusion distribution of patients with non-small cell lung cancer.

METHODS

Sixty patients with lung cancer, who were deemed operable, were randomly allocated into two groups. Intensive physical therapy was performed in patients in the study group before operation. Both groups received routine physical therapy after operation.

RESULTS

There was no difference in pulmonary function tests between the two groups. Intensive physical therapy statistically significantly increased peripheral blood oxygen saturation. At least one complication was noted in 5 patients (16.7%) in the control group, and 2 (6.7%), in the study group. However, there was no statistically significant difference (p = 0,4). The hospital stay has been found to be statistically significantly shortened by intensive physical therapy (p <0.001). Ventilation-perfusion distribution was found to be significantly effected by intensive physical therapy. The change was prominent in the the contralateral lung (p <0.001).

CONCLUSIONS

Intensive physical therapy appeared to increase oxygen saturation, reduce hospital stay, and change the ventilation/perfusion distribution. It had a significant, positive effect on the exercise capacity of patients.

摘要

背景

我们计划研究术前短期强化物理治疗对非小细胞肺癌患者肺功能、气体交换、弥散能力及通气-灌注分布的影响。

方法

将60例被认为可手术的肺癌患者随机分为两组。研究组患者在术前进行强化物理治疗。两组患者术后均接受常规物理治疗。

结果

两组患者的肺功能测试结果无差异。强化物理治疗使外周血氧饱和度有统计学意义的显著升高。对照组有5例患者(16.7%)至少出现1种并发症,研究组有2例患者(6.7%)出现并发症。然而,差异无统计学意义(p = 0.4)。强化物理治疗使住院时间有统计学意义的显著缩短(p <0.001)。强化物理治疗对通气-灌注分布有显著影响。对侧肺的变化尤为明显(p <0.001)。

结论

强化物理治疗似乎可提高血氧饱和度、缩短住院时间并改变通气/灌注分布。对患者的运动能力有显著的积极影响。

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