酵母细胞壁颗粒：一类有前途的、受自然启发的微载体，可用于多模式成像。
Yeast cell wall particles: a promising class of nature-inspired microcarriers for multimodal imaging.
机构信息
Department of Life Sciences, Faculty of Sciences and Technology, and Center for Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal.
出版信息
Chem Commun (Camb). 2011 Oct 14;47(38):10635-7. doi: 10.1039/c1cc14019a. Epub 2011 Sep 1.
PMID:21881668
Abstract
This communication demonstrates that yeast cell wall particles (YCWPs) are a promising class of nature-inspired biocompatible microcarriers for the delivery of amphipathic/lipophilic imaging reporters. When a paramagnetic MRI agent is loaded, the longitudinal relaxivity per particle at 0.5 T is the highest ever reported for Gd-based systems.
摘要
本研究表明酵母细胞壁颗粒（YCWPs）是一类很有前途的、受自然启发的、生物相容性的微载体，可用于递呈两亲性/亲脂性的成像报告分子。当负载顺磁性 MRI 造影剂时，在 0.5T 下每颗粒的纵向弛豫率比以往报道的基于 Gd 的系统都要高。
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