De Mercato R, Perna E, Oriani G, Siciliano V, Iovinella V, Ciampi R, Bassi A, Tagliaferro R
II Facoltà di Medicina, Università degli Studi di Napoli.
Minerva Med. 1990 Apr;81(4):271-3.
Serum beta 2-microglobulin levels (beta-2-M) were studied in 150 drug addicts, 50 of them asymptomatic carriers of anti HIV-1 antibodies, 50 symptomatic carriers with persistent generalized lymphadenopathy (P.G.L.) and 50 serum negative patients who had been living in a closed community for at least 2 years. The results showed increased beta-2-M in 24 P.G.L. patients (48%), in 6 of the asymptomatic serum positive cases (12%) and in 3 of the serum negative subjects (6%). No such increase was found in the selected control group. Statistical analysis using the chi-square test and one-way variance analysis gave a significant result. The data suggest that increased serum beta-2-M is essentially linked to the presence of P.G.L.
对150名吸毒者的血清β2-微球蛋白水平（β-2-M）进行了研究，其中50名是抗HIV-1抗体无症状携带者，50名是有持续性全身性淋巴结肿大（P.G.L.）的有症状携带者，50名血清阴性患者，他们在封闭社区生活至少2年。结果显示，24名P.G.L.患者（48%）、6名无症状血清阳性病例（12%）和3名血清阴性受试者（6%）的β-2-M升高。在选定的对照组中未发现此类升高。使用卡方检验和单因素方差分析进行的统计分析得出了显著结果。数据表明，血清β-2-M升高主要与P.G.L.的存在有关。
