Winters Jeffrey L
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA.
J Clin Apher. 2011;26(5):239-42. doi: 10.1002/jca.20307. Epub 2011 Aug 31.
The quality of evidence supporting the use of apheresis in the treatment of individual diseases and disorders is often limited. For most diseases and disorders, randomized controlled trials of the use of apheresis have not been performed and for many, due to rarity of the condition, it is unlikely that they will ever be performed. In keeping with its vision, the American Society for Apheresis (ASFA) has created and regularly updated guidelines on the use of apheresis in the treatment of disease. These guidelines seek to summarize the literature on the use of apheresis in treating diseases, provide a critical review of this literature, and give practical guidance to apheresis practitioners. The most recent ASFA guidelines were published in 2010. This article reviews the history of the ASFA guidelines, the changes that were made in the 2010 guidelines, and future directions and plans for these guidelines. The 2010 ASFA guidelines on the use of therapeutic apheresis in clinical practice represent the state of the art in apheresis medicine in 2010.
支持采用血液分离术治疗个别疾病和病症的证据质量往往有限。对于大多数疾病和病症而言，尚未开展关于使用血液分离术的随机对照试验，而且对于许多疾病，由于病情罕见，不太可能开展此类试验。为了与自身愿景保持一致，美国血液分离学会（ASFA）制定并定期更新了关于血液分离术在疾病治疗中应用的指南。这些指南旨在总结有关血液分离术治疗疾病的文献，对该文献进行批判性综述，并为血液分离术从业者提供实用指导。ASFA的最新指南于2010年发布。本文回顾了ASFA指南的历史、2010年指南所做的更改以及这些指南未来的方向和计划。2010年ASFA关于治疗性血液分离术在临床实践中应用的指南代表了2010年血液分离术医学的最新水平。
