Stastná R, Karasová L, Svácek J, Petrásek R, Winkler L, Lánská V, Skála I, Malý J
Research Department of Medicine, Institute for Clinical and Experimental Medicine, Prague, Czechoslovakia.
Pancreas. 1990 May;5(3):358-60. doi: 10.1097/00006676-199005000-00018.
In 14 nonobese patients after acute pancreatitis and with normal oral glucose tolerance, the response of insulin, C-peptide, and pancreatic glucagon after 100 g of oral glucose was assessed. The curves of insulin and C-peptide were significantly raised compared with those of controls, and no difference was found between the response of patients with a negative (n = 8) and a positive (n = 6) family history of type II diabetes. The curves of pancreatic glucagon did not differ from those found in controls. Our results indicate that a normal response to glucose after recovery from an attack of acute pancreatitis is maintained at the cost of increased insulin secretion.
在14例急性胰腺炎后非肥胖且口服葡萄糖耐量正常的患者中，评估了口服100克葡萄糖后胰岛素、C肽和胰高血糖素的反应。与对照组相比，胰岛素和C肽曲线显著升高，且2型糖尿病家族史阴性（n = 8）和阳性（n = 6）的患者之间的反应没有差异。胰高血糖素曲线与对照组无差异。我们的结果表明，急性胰腺炎发作恢复后对葡萄糖的正常反应得以维持，但代价是胰岛素分泌增加。
