Center for Pregnant Women with Diabetes, Rigshospitalet Department of Endocrinology, Copenhagen, Denmark.
Diabet Med. 2012 Feb;29(2):272-7. doi: 10.1111/j.1464-5491.2011.03426.x.
To evaluate self-reported satisfaction and barriers to initiating real-time continuous glucose monitoring in early pregnancy among women with pregestational diabetes.
Fifty-four women with Type 1 diabetes and 14 women with Type 2 diabetes were offered continuous glucose monitoring for 6 days at median 9 (range 6-14) gestational weeks and were asked to answer a semi-structured questionnaire on patient satisfaction.
Median HbA1c was 49 (range 34-86) mmol/mol) [6.6 (5.3-10.0) %] and duration of diabetes was 12 (0.5-37) years. Continuous glucose monitoring was used for 6 (0.5-7) days, with 43 (65%) women using continuous glucose monitoring for at least 5 days. The women experienced 2.7 (0-12) alarms per 24 h, of which approximately one third was technical alarms and one third disturbed their sleep. Sixteen women (24%) reported discomfort with continuous glucose monitoring during daytime and twelve (18%) during sleep. Many women reported improved diabetes understanding (52%) and would recommend continuous glucose monitoring to others (83%). Twenty-four patients (36%) had continuous glucose monitoring removed earlier than planned ( before the intended 6 days of initial monitoring). Ten women (15%) did not wish to use continuous glucose monitoring again in pregnancy. Main causes behind early removal of continuous glucose monitoring were self-reported skin irritation, technical problems and continuous glucose monitoring inaccuracy. No differences were found in continuous glucose monitoring use, inconvenience or compliance with respect to diabetes type.
The majority of pregnant women with diabetes found real-time continuous glucose monitoring useful and the intervention was equally tolerated regardless of diabetes type. Nevertheless, continuous glucose monitoring was frequently removed earlier than planned, primarily because of skin irritation, technical problems and inaccuracy.
评估妊娠早期孕前糖尿病女性实时连续血糖监测启动的自我报告满意度和障碍。
54 例 1 型糖尿病和 14 例 2 型糖尿病女性在妊娠中位数 9（范围 6-14）周时接受连续血糖监测 6 天，并被要求回答一份关于患者满意度的半结构式问卷。
中位糖化血红蛋白（HbA1c）为 49（范围 34-86）mmol/mol）[6.6（5.3-10.0）%]，糖尿病病程为 12（0.5-37）年。连续血糖监测使用了 6（0.5-7）天，43（65%）名女性使用连续血糖监测至少 5 天。女性每 24 小时经历 2.7（0-12）次报警，其中约三分之一为技术报警，三分之一干扰睡眠。16 名女性（24%）报告白天使用连续血糖监测时有不适，12 名女性（18%）在睡眠期间有不适。许多女性报告说对糖尿病的理解有所提高（52%），并会向他人推荐连续血糖监测（83%）。24 名患者（36%）比计划提前（在最初 6 天的连续监测之前）移除了连续血糖监测。10 名女性（15%）不想在妊娠期间再次使用连续血糖监测。提前移除连续血糖监测的主要原因是自我报告的皮肤刺激、技术问题和连续血糖监测不准确。未发现连续血糖监测使用、不便或对糖尿病类型的依从性存在差异。
大多数妊娠糖尿病女性认为实时连续血糖监测有用，并且无论糖尿病类型如何，该干预措施都能得到同等耐受。然而，连续血糖监测经常比计划提前移除，主要是由于皮肤刺激、技术问题和不准确。
