Baig W W, Attur R P, Chawla A, Reddy S, Pillai S, Rao L, Rao G, Ashok K, Yegneswaran P
Department of Nephrology, Kasturba Medical College, Manipal, Karnataka, India.
Transpl Infect Dis. 2011 Oct;13(5):489-91. doi: 10.1111/j.1399-3062.2011.00660.x. Epub 2011 Aug 26.
An unusual case of epididymal and prostatic histoplasmosis is reported from Karnataka State of southern India, in a 37-year-old male renal transplant recipient, who had presented with gastrointestinal histoplasmosis a year before the second presentation and had responded successfully to 9 months' treatment with itraconazole. The patient presented a second time with high-grade fever and pain in the scrotum and the lower abdomen. Ultrasound of the abdomen revealed a retrotrigonal abscess, which was confirmed on computed tomography scan of the pelvis. Pus was drained via transrectal route and biopsy specimens were taken from the epididymis and the prostate. Histopathology revealed the picture suggestive of histoplasmosis, and the pus on culture confirmed the infection with Histoplasma capsulatum. To our knowledge, only 5 cases of epididymal histoplasmosis have been reported in the literature, our case being the second report from India and sixth in the world; prostatic histoplasmosis is also a rare occurrence.
印度南部卡纳塔克邦报告了一例不寻常的附睾和前列腺组织胞浆菌病病例,患者为一名37岁的男性肾移植受者,在第二次就诊前一年曾患胃肠道组织胞浆菌病,接受伊曲康唑9个月治疗后成功康复。患者第二次就诊时出现高热以及阴囊和下腹部疼痛。腹部超声显示膀胱三角后脓肿,盆腔计算机断层扫描证实了这一情况。通过经直肠途径引流脓液,并从附睾和前列腺采集活检标本。组织病理学显示有组织胞浆菌病的迹象,培养的脓液证实感染了荚膜组织胞浆菌。据我们所知,文献中仅报道了5例附睾组织胞浆菌病病例,我们的病例是印度的第二例报告,也是世界上第六例;前列腺组织胞浆菌病也很少见。