Department of General and Digestive Surgery, Colorectal Unit, Bellvitge University Hospital, University of Barcelona and IDIBELL, Barcelona, Spain.
Colorectal Dis. 2012 Mar;14(3):e95-e102. doi: 10.1111/j.1463-1318.2011.02798.x.
Surgical site infection (SSI) is the most common cause of morbidity after colorectal surgery. The aim of this study was to analyze risk factors for SSI in patients who had undergone surgery for rectal cancer.
A multicentre observational study was carried out on 2131 patients operated on for rectal cancer between May 2006 and May 2009. Twenty-nine centres were involved. SSI included wound infection and organ space infection within 30 days after the operation. Univariate and multivariate analyses were carried out to study possible risk factors for SSI.
Wound infection and organ space infection were diagnosed in 8.9% and 10%, respectively, of patients. The anastomotic leakage rate was 8%. Multivariate analysis showed that wound infection was related to tumour stage, a converted laparoscopic procedure and open surgery. Organ space infection was related to Stage IV tumour, a tumour < 11 cm from the anal verge, low anterior resection and Hartmann's procedure.
Rectal surgery for malignant disease is associated with a considerable rate of SSI. Wound infection and organ space infection are related to different factors and therefore should be evaluated separately.
手术部位感染（SSI）是结直肠手术后发病率最高的原因。本研究旨在分析接受直肠癌手术患者 SSI 的危险因素。
对 2006 年 5 月至 2009 年 5 月期间接受直肠癌手术的 2131 例患者进行了一项多中心观察性研究。涉及 29 个中心。SSI 包括术后 30 天内的伤口感染和器官间隙感染。对可能的 SSI 危险因素进行了单因素和多因素分析。
分别有 8.9%和 10%的患者发生伤口感染和器官间隙感染。吻合口漏的发生率为 8%。多因素分析显示，伤口感染与肿瘤分期、腹腔镜转为开腹手术和开放性手术有关。器官间隙感染与 IV 期肿瘤、距肛缘<11cm 的肿瘤、低位前切除术和 Hartmann 手术有关。
恶性疾病的直肠手术与相当高的 SSI 发生率有关。伤口感染和器官间隙感染与不同的因素有关，因此应分别进行评估。
