Department of Child and Adolescent Neurology, Psychiatry and Rehabilitation, Sapienza University of Rome, Italy.
Headache. 2011 Sep;51(8):1212-27. doi: 10.1111/j.1526-4610.2011.01978.x.
Medication-overuse headache (MOH) refers to headache attributed to excessive use of acute medications. The role of personality needs studies to explain the shifting from drug use to drug abuse. The main aim of this study is to study personality, according to Minnesota Multiphasic Personality Inventory, comparing MOH, episodic headache, substance addicts (SA) vs healthy controls.
Eighty-two MOH patients (mean age 44.5; 20 M, 62 F) and 35 episodic headache (mean age 40.2; 8 M, 27 F), were compared to 37 SA (mean age 32.5; 29 M, 8 F) and 37 healthy controls (mean age: 32.49; 20 M, 17 F). International Classification of Headache Disorders 2nd Edition criteria were employed. Chi-square test, Kruskal-Wallis test, and post hoc comparisons were used for statistics.
MOH patients scored higher on Hypochondriasis, Depression (only females), Hysteria (only females) (P < .000). MOH did not show higher scores than episodic headache or healthy controls in dependency scales, while SA did.
The data obtained show that MOH and SA do not share common personality characteristics linked to dependence. Although further studies are needed to understand if such a difference is related to instrumental characteristics or to yet undiscovered psychobiological characteristics of MOH patients; however, we hypothesize that the detected difference may rely on the fact that drug dependence in the 2 groups is promoted by entirely different needs: pleasure seeking in the SA group, pain avoidance in the MOH group.
药物过度使用性头痛（MOH）是指由于过度使用急性药物而引起的头痛。个性的作用需要研究来解释从药物使用到药物滥用的转变。本研究的主要目的是根据明尼苏达多相人格问卷（MMPI）研究人格，比较偏头痛、发作性头痛、物质滥用者（SA）与健康对照组。
82 例 MOH 患者（平均年龄 44.5 岁；男 20 例，女 62 例）和 35 例发作性头痛（平均年龄 40.2 岁；男 8 例，女 27 例）与 37 例 SA（平均年龄 32.5 岁；男 29 例，女 8 例）和 37 例健康对照组（平均年龄：32.49 岁；男 20 例，女 17 例）进行比较。采用国际头痛疾病分类第 2 版标准。采用卡方检验、Kruskal-Wallis 检验和事后比较进行统计学分析。
MOH 患者在疑病症、抑郁（仅女性）、癔症（仅女性）方面的得分较高（P<0.000）。MOH 在依赖量表上的得分并不高于发作性头痛或健康对照组，而 SA 则高于这两组。
获得的数据表明，MOH 和 SA 没有共享与依赖相关的共同人格特征。尽管需要进一步研究来了解这种差异是否与工具性特征或尚未发现的 MOH 患者的心理生物学特征有关；然而，我们假设所检测到的差异可能取决于这样一个事实，即两组的药物依赖是由完全不同的需求引起的：SA 组是寻求快感，MOH 组是避免疼痛。
