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[皮肤病学中的细胞学方法]

[Cytologic methods in dermatology].

作者信息

Haneke E, Vigneswaran N

机构信息

Hautklinik, Ferdinand-Sauerbruch-Klinikum Wuppertal.

出版信息

Z Hautkr. 1990 Feb;65(2):154, 157-60, 163-6.

PMID:2188453
Abstract

Cytology is a simple, fast, and inexpensive procedure yielding a high degree of diagnostic accuracy-provided the examiner has a good deal of experience. It has not yet become generally accepted in the diagnosis of skin diseases, since biopsies are very easy to perform, and histopathology is still more reliable than cytology. Modern techniques such as electron microscopy, immunofluorescence, immunocytochemistry with polyclonal and monoclonal antibodies, immunoelectron microscopy, DNA flow cytometry, and in situ hybridization have considerably increased the potentials of cytology and will certainly help to win general recognition in dermatology, as well.

摘要

细胞学是一种简单、快速且成本低廉的检查方法,只要检查者经验丰富,就能获得高度准确的诊断结果。由于皮肤活检操作非常简便,且组织病理学的诊断结果仍比细胞学更可靠,因此细胞学在皮肤病诊断中尚未得到广泛认可。电子显微镜、免疫荧光、使用多克隆和单克隆抗体的免疫细胞化学、免疫电子显微镜、DNA流式细胞术以及原位杂交等现代技术,极大地提升了细胞学的应用潜力,也必将有助于其在皮肤病学领域获得广泛认可。

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