School of Nursing, Midwifery and Social Care, Edinburgh Napier University, Edinburgh, UK.
J Clin Nurs. 2011 Dec;20(23-24):3423-9. doi: 10.1111/j.1365-2702.2011.03771.x. Epub 2011 Sep 2.
To enable people with Type 1 diabetes to exercise safely by investigating the reproducibility of the glucose response to an algorithm for carbohydrate and insulin adjustment during and after exercise compared to their self-management strategies.
Difficulties in managing blood glucose levels in Type 1 diabetes whilst exercising is known to deter people from exercise. Currently there is a limited evidence base to aid health care professionals enable people with diabetes to exercise safely. This study seeks to address this gap.
A quasi-experimental study was undertaken amongst people with Type 1 diabetes.
Over 14 days, 14 participants undertook four exercise sessions (40 minutes at 50%VO2max). Two sessions were undertaken in week 1 self-managing their diabetes and two sessions in week 2 using an algorithm for carbohydrate and insulin adjustment.
The mean reduction of glucose levels detected by Continuous Glucose Monitoring during exercise was 3·1 (SD 2·03) mmol/l. Time spent within the range of 4-9 mmol/l during exercise was not significantly different between the self-managed and the algorithm weeks (-3-22·4 min). The mean reduction of blood glucose for each individual over all four exercise sessions ranged between 0·8-5·95 mmol/l. The technical error between days one and two was 2·4 mmol/l (CV=33·2%) and between days 3-4 the technical error was 2·7 mmol/l (CV=33·7%).
The results provide useful data about the reproducibility of the blood glucose response to moderate intensity exercise, despite the variability of individual responses 40 minutes of moderate intensity exercise decreases Continuous Glucose Monitoring glucose by 3 mmol/l with or without a 30% decrease of insulin before exercise.
This information provides valuable baseline information for people with diabetes and health care professionals who wish to encourage physical activity and undertake further research in this area.
通过调查算法在运动中和运动后调整碳水化合物和胰岛素以适应 1 型糖尿病患者的葡萄糖反应与他们的自我管理策略相比的可重复性，使 1 型糖尿病患者能够安全地进行运动。
众所周知，1 型糖尿病患者在运动中难以控制血糖水平，这会阻止他们进行运动。目前，帮助医疗保健专业人员使糖尿病患者安全运动的证据有限。本研究旨在解决这一差距。
在 1 型糖尿病患者中进行了一项准实验研究。
在 14 天内，14 名参与者进行了 4 次运动（40 分钟，50%VO2max）。2 次在第 1 周自我管理糖尿病，2 次在第 2 周使用碳水化合物和胰岛素调整算法。
连续血糖监测仪在运动中检测到的葡萄糖水平平均降低 3.1（SD 2.03）mmol/L。在自我管理和算法周之间，运动期间血糖处于 4-9mmol/L 范围内的时间没有显著差异（-3-22.4 分钟）。在所有 4 次运动中，每位个体的血糖平均降低范围在 0.8-5.95mmol/L 之间。第 1 天和第 2 天之间的技术误差为 2.4mmol/L（CV=33.2%），第 3-4 天之间的技术误差为 2.7mmol/L（CV=33.7%）。
尽管个体反应存在差异，但结果提供了有关中等强度运动对血糖反应可重复性的有用数据，40 分钟的中等强度运动可使连续血糖监测仪的血糖降低 3mmol/L，或在运动前降低 30%的胰岛素。
这些信息为糖尿病患者和希望鼓励身体活动并在该领域进行进一步研究的医疗保健专业人员提供了有价值的基线信息。
