Panteleeva G A
Vestn Dermatol Venerol. 1990(2):50-2.
The author analyzes the clinical data and paraclinical characteristics of patients with paraneoplastic bullous dermatoses, followed up at the Research Institute of Skin and Sexually Transmitted Diseases in the town of Gorki since 1980. Clinical features of Duhring's paraneoplastic dermatoses were detected, consisting in dissemination of the process with involvement of facial skin and with essential itching. Paraclinical characteristics are as follows: neither eosinophils, nor acantholytic cells are detectable in the vesicular contents, Jadassohn's test is negative, histomorphologic examination shows intraepidermal localization of the vesicle. In paraneoplastic pemphigus involvement of the mucosae alone was recorded, and the painful syndrome whose severity did not correlate with the depth of the pathologic foci; corticosteroid therapy has proved ineffective. The author recommends thorough examinations of patients with bullous dermatoses if they present with the aforesaid clinical and paraclinical characteristics.
作者分析了自1980年以来在高尔基市皮肤与性传播疾病研究所随访的副肿瘤性大疱性皮肤病患者的临床资料和临床旁特征。检测到杜林副肿瘤性皮肤病的临床特征，包括病情播散累及面部皮肤并伴有剧烈瘙痒。临床旁特征如下：水疱内容物中未检测到嗜酸性粒细胞和棘层松解细胞，雅达松试验阴性，组织形态学检查显示水疱位于表皮内。在副肿瘤性天疱疮中，仅记录到黏膜受累，且疼痛综合征的严重程度与病理病灶深度无关；皮质类固醇治疗已证明无效。作者建议，如果大疱性皮肤病患者出现上述临床和临床旁特征，应对其进行全面检查。
