Department of Chemistry, University of Science & Technology of China, Hefei 230026, China.
Biotechnol Adv. 2011 Nov-Dec;29(6):972-82. doi: 10.1016/j.biotechadv.2011.08.012. Epub 2011 Aug 22.
Recovery of bioenergy and biochemicals from wastewater has attracted growing and widespread interests. In this respect, two-stage bioconversion process (TSBP) offers an appealing avenue to achieve stepwise and directional substrate conversion in separated stages. Such a biosystem not only enables enhanced degradation of organics, but also favors a high product yield and quality. Various TSBRs have been developed for the production of methane, hydrogen, electricity, bioplastics, bioflocculants, biopesticides, biosurfactants and other value-added products, demonstrating marked advantages over the conventional one-stage processes. It represents a promising, and likely the sole viable, paradigm for future application. However, there are also many remaining challenges. This paper provides an overview of the various TSBPs, introduces the recent advances, and discusses the major challenges and the future perspectives for practical application.
从废水中回收生物能源和生物化学物质引起了越来越多的关注。在这方面，两段式生物转化工艺（TSBP）提供了一种有吸引力的途径，可以在分离的阶段中逐步和定向地进行底物转化。这样的生物系统不仅能够增强有机物的降解，而且有利于获得高的产物产率和质量。已经开发了各种 TSBR 用于生产甲烷、氢气、电力、生物塑料、生物絮凝剂、生物农药、生物表面活性剂和其他增值产品，与传统的单阶段工艺相比具有显著的优势。它代表了一种有前途的、可能是唯一可行的未来应用范例。然而，仍然存在许多挑战。本文概述了各种两段式生物转化工艺，介绍了最新进展，并讨论了实际应用的主要挑战和未来展望。
