Gene Regulation Laboratory, Genome Institute of Singapore, Singapore 138672.
Cell Stem Cell. 2011 Sep 2;9(3):181-3. doi: 10.1016/j.stem.2011.08.003.
The forkhead box O (FoxO) family is involved in diverse cellular processes such as tumor suppression, stress response, and metabolism. In a recent Nature Cell Biology Letter, Zhang et al. (2011) uncover a novel role for FoxO proteins in regulating the identity of human ESCs.
叉头框 O(FoxO)家族参与多种细胞过程,如肿瘤抑制、应激反应和代谢。在最近的《自然细胞生物学通讯》中,Zhang 等人(2011)揭示了 FoxO 蛋白在调节人类胚胎干细胞特性方面的新作用。