丁螺环酮增强氟西汀治疗强迫症的疗效
Buspirone augmentation of fluoxetine in obsessive-compulsive disorder.
作者信息
Markovitz P J, Stagno S J, Calabrese J R
机构信息
Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH.
出版信息
Am J Psychiatry. 1990 Jun;147(6):798-800. doi: 10.1176/ajp.147.6.798.
PMID:2188516
Abstract
Eleven obsessive-compulsive patients underwent a prospective open-label trial of fluoxetine monotherapy followed by buspirone augmentation. The combination therapy was statistically superior to fluoxetine monotherapy. The results point to the importance of the 5-HT1a receptor in obsessive-compulsive disorder.
摘要
11名强迫症患者接受了一项前瞻性开放标签试验，先进行氟西汀单一疗法，随后使用丁螺环酮增效。联合疗法在统计学上优于氟西汀单一疗法。结果表明5-HT1a受体在强迫症中的重要性。
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