Department of Neurophysiology, Danish Epilepsy Centre, Dianalund, Denmark.
Epilepsy Res. 2011 Nov;97(1-2):142-5. doi: 10.1016/j.eplepsyres.2011.07.016. Epub 2011 Aug 31.
Cathodal transcranial direct current stimulation (tDCS) decreases cortical excitability. The purpose of the study was to investigate whether cathodal tDCS could interrupt the continuous epileptiform activity. Five patients with focal, refractory continuous spikes and waves during slow sleep were recruited. Cathodal tDCS and sham stimulation were applied to the epileptic focus, before sleep (1 mA; 20 min). Cathodal tDCS did not reduce the spike-index in any of the patients.
阴极经颅直流电刺激（tDCS）降低皮质兴奋性。本研究旨在探讨阴极 tDCS 是否可以中断持续性癫痫样活动。招募了 5 例有局灶性、难治性慢波睡眠期连续棘波和尖波的患者。在睡眠前（1 mA；20 分钟）将阴极 tDCS 和假刺激应用于癫痫病灶。在任何患者中，阴极 tDCS 均未降低棘波指数。
