Canver Charles C, Al Buraiki Jehad A, Saad Elias, Yousafzai Sajjad M, Al Ahmadi Mamdouh D, Al Sanei Aly M
King Faisal Heart Institute, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Asian Cardiovasc Thorac Ann. 2011 Jun;19(3-4):244-8. doi: 10.1177/0218492311408732.
Cardiac transplants are performed sporadically or not at all in the majority of predominantly Muslim countries in the Middle East. We examined our experience in 76 patients who underwent heart transplantation between January 2005 and May 2010 in our center in Saudi Arabia. Excluded were 50 transplants performed between 1989 and 2004, due to incomplete data. Primary outcomes were complications, 30-day and late mortality rates, and 1-year survival. The heart transplant activity between 2005 and 2010 (15.0 per year) was 4.5-fold higher than that between 1989 and 2004 (3.3 per year). There were 61 (80%) men and 15 (20%) women, with a mean age of 35 years (range, 13-57 years). The mean waiting list time was 64 days (range, 1-262 days), and hospital stay was 30 days (range, 12-166 days). Major complications were infection (10), low-grade rejection (9), reoperation for hemorrhage (8), and sternal dehiscence (2). The 30-day mortality was 7.8% (6/76). Actuarial survival was 87.4% at 1 year and 81.5% at 3 years. A hospital in a Muslim country can increase cardiac transplant activity with excellent 30-day mortality and early survival comparable to that in worldwide counterparts.
在中东地区大多数以穆斯林为主的国家，心脏移植手术只是偶尔进行，甚至根本不开展。我们回顾了2005年1月至2010年5月期间在沙特阿拉伯我们中心接受心脏移植的76例患者的情况。由于数据不完整，排除了1989年至2004年期间进行的50例移植手术。主要观察指标为并发症、30天和晚期死亡率以及1年生存率。2005年至2010年期间的心脏移植手术量（每年15.0例）是1989年至2004年期间（每年3.3例）的4.5倍。患者中有61名（80%）男性和15名（20%）女性，平均年龄为35岁（范围13 - 57岁）。平均等待名单时间为64天（范围1 - 262天），住院时间为30天（范围12 - 166天）。主要并发症包括感染（10例）、轻度排斥反应（9例）、因出血再次手术（8例）和胸骨裂开（2例）。30天死亡率为7.8%（6/76）。1年精算生存率为87.4%，3年为81.5%。在一个穆斯林国家的医院可以提高心脏移植手术量，且30天死亡率和早期生存率良好，与全球其他同类医院相当。
