Department of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Retina. 2012 Jan;32(1):127-33. doi: 10.1097/IAE.0b013e318214d094.
To determine whether the axial length (AL) in highly myopic normal adult eyes with myopic complications in the fellow eyes increases significantly during a 1-year interval and to investigate the relationships between the changes in the AL and different ocular parameters.
The medical records of 20 highly myopic normal eyes whose fellow eyes had myopic complications were reviewed. The AL, subfoveal choroidal thickness, height of a posterior staphyloma, and length of the retinal pigment epithelium from the fovea to 3-mm superior, inferior, nasal, and temporal retina were measured twice at an interval of approximately 1 year. The changes in these ocular parameters and their correlations were investigated.
The AL increased, the choroid became thinner (both P < 0.001), the superior (P < 0.05) and temporal (P < 0.01) staphyloma height increased, and the superior and temporal retinal pigment epithelial length increased (both P < 0.01). All the changes were significant. Stepwise analyses indicated that the factor most associated with the increase in the AL was the increase in the superior retinal pigment epithelial length (P < 0.001).
Our results indicate that the AL can increase significantly in highly myopic normal adult eyes during a 1-year interval, and the increase in the posterior staphyloma height is the most likely cause for the increased AL.
确定伴有对侧眼近视并发症的高度近视正常成年人眼的眼轴（AL）在 1 年内是否显著增加，并探讨 AL 变化与不同眼部参数之间的关系。
回顾了 20 只高度近视正常眼的病历，这些眼的对侧眼有近视并发症。在大约 1 年的时间间隔内，两次测量 AL、黄斑下脉络膜厚度、后葡萄肿高度、以及从黄斑到 3mm 上、下、鼻、颞视网膜的视网膜色素上皮长度。研究了这些眼部参数的变化及其相关性。
AL 增加，脉络膜变薄（均 P < 0.001），上（P < 0.05）和颞（P < 0.01）葡萄肿高度增加，以及上和颞视网膜色素上皮长度增加（均 P < 0.01）。所有变化均有统计学意义。逐步分析表明，与 AL 增加最相关的因素是上视网膜色素上皮长度的增加（P < 0.001）。
我们的结果表明，高度近视正常成年人眼的 AL 在 1 年内可显著增加，后葡萄肿高度的增加是 AL 增加的最可能原因。
