Uyar Meral, Vrt Osman, Bayram Nazan, Elbek Osman, Savaş Esen, Altindağ Abdurrahman, Ozçalşkan Deniz, Ozsaraç Ilker, Gündoğdu Nevhiz, Savaş Haluk A
Department of Pulmonary Medicine, University of Gaziantep, Turkey.
South Med J. 2011 Jul;104(7):495-8. doi: 10.1097/SMJ.0b013e31821fbfb0.
Psychiatric disorders are common in obstructive sleep apnea syndrome (OSAS); however, interrelating factors influencing psychiatric comorbidity (PC) in OSAS are unclear. The aim of this study is to investigate gender related differences with PC in OSAS.
Data of patients diagnosed as OSAS in University of Gaziantep from January 2006 to January 2010 were retrospectively evaluated. Polysomnographic data were recorded with Viasys Sleep Screen (Viasys Healthcare, Germany). Patients younger than 18 years old were excluded.
PC was present in 53.1% of OSAS patients. The rate of male subjects with PC was 42.6%; however, 76.26% of females had PC (P = 0.00). Age (P = 0.00) and body mass index (BMI) (P = 0.00) were higher in patients with PC. Ferritin levels were lower in patients with PC (P = 0.00). Male subjects with PC were older and had lower sleep efficiency and longer rapid eye movement latency than males without PC. BMI was the only contributory factor to PC in female subjects.
PC in OSAS is common, especially in females. Apnea hypopnea index does not seem to influence probability of PC.
精神障碍在阻塞性睡眠呼吸暂停综合征（OSAS）中很常见；然而，影响OSAS中精神共病（PC）的相关因素尚不清楚。本研究的目的是调查OSAS中与PC相关的性别差异。
回顾性评估2006年1月至2010年1月在加济安泰普大学被诊断为OSAS的患者的数据。使用Viasys睡眠监测仪（德国Viasys医疗保健公司）记录多导睡眠图数据。排除年龄小于18岁的患者。
53.1%的OSAS患者存在PC。患有PC的男性受试者比例为42.6%；然而，76.26%的女性患有PC（P = 0.00）。患有PC的患者年龄（P = 0.00）和体重指数（BMI）（P = 0.00）更高。患有PC的患者铁蛋白水平较低（P = 0.00）。患有PC的男性受试者比没有PC的男性年龄更大，睡眠效率更低，快速眼动潜伏期更长。BMI是女性受试者中PC的唯一促成因素。
OSAS中的PC很常见，尤其是在女性中。呼吸暂停低通气指数似乎不影响PC的可能性。
