Klotchko Alyona, Wallace Mark R, Licitra Carmelo, Sieger Barry
Department of Internal Medicine, Orlando Health, FL, USA.
South Med J. 2011 Jul;104(7):509-14. doi: 10.1097/SMJ.0b013e31821e91b1.
To evaluate the clinical relevance and impact of an emerging bacterial pathogen, Staphylococcus lugdunensis, in a large teaching hospital.
Three-year retrospective microbiological and clinical review of all S. lugdunensis isolates from a single medical center.
Seventy-seven isolates were identified; 70 had complete data. Soft tissue, bone, joint, central nervous system, urine and bloodstream infections occurred. Soft tissue infections were primarily abscesses. There were four infections of prosthetic joints and nine cases of osteomyelitis. There were 21 bacteremias, 5 of which were associated with endocarditis; 2 died. Most isolates were penicillin resistant.
S. lugdunensis has emerged as a major human pathogen, capable of causing significant infections at many sites. It should never be dismissed as a contaminant without careful review.
评估一种新出现的细菌病原体——路邓葡萄球菌在一家大型教学医院中的临床相关性及影响。
对来自单一医疗中心的所有路邓葡萄球菌分离株进行为期三年的回顾性微生物学和临床研究。
共鉴定出77株分离株；70株有完整数据。发生了软组织、骨骼、关节、中枢神经系统、尿液及血流感染。软组织感染主要为脓肿。有4例人工关节感染和9例骨髓炎病例。有21例菌血症，其中5例与心内膜炎相关；2例死亡。大多数分离株对青霉素耐药。
路邓葡萄球菌已成为一种主要的人类病原体，能够在多个部位引起严重感染。在未经仔细评估的情况下，绝不应将其视为污染物而不予理会。
