Mishra Aparajita, Tripathi Kalpalata, Mohanty Lity, Pujari Sujata
Department of Pathology, S.C.B. Medical College, Cuttack, 753007 Orissa India.
Indian J Hematol Blood Transfus. 2010 Sep;26(3):109-10. doi: 10.1007/s12288-010-0042-2. Epub 2010 Oct 2.
Philadelphia chromosome (Ph(1))-positive Chronic Myelogenous Leukemia (CML) in a child below the age of 3 years is extremely rare. We have reported such a case in a 3 year old male child. Peripheral blood smear revealed features of CML and karyotypic study showed (Ph(1)) positivity. Biologic behaviour and prognosis are similar to that of adult-type of CML.
3岁以下儿童的费城染色体（Ph(1)）阳性慢性粒细胞白血病（CML）极为罕见。我们报告了1例3岁男童的此类病例。外周血涂片显示CML特征，核型研究显示（Ph(1)）阳性。生物学行为和预后与成人型CML相似。
