Zawar Vijay, Chuh Antonio, Sankalecha Sudhir
Department of Dermatology, NDMVPS Medical College, Nashik, India.
J Dermatol Case Rep. 2007 Dec 29;1(1):10-5. doi: 10.3315/jdcr.2007.1.1003.
We report a retrospective case-control study to investigate whether the rotundiform variant of pityriasis versicolor (PV) is significantly associated with the first episodes of PV. Our setting was a dermatology clinic run by a consultant dermatologist. We retrieved medical records of all patients with PV between April 1, 2002 and March 31, 2005. We identified patients with lesions forming closed round circles. We excluded patients with uncertain diagnosis or diagnosis not substantiated by Wood's light examination or skin scrapings for potassium hydroxide examination. For each patient, we retrieved the medical record of the next patient of the same sex and similar age (± three years) with documented non-rotundiform PV and diagnosis substantiated by investigations as the control subject.80 patients were diagnosed as having PV during the record retrieval period. 18 had clinical descriptions or clinical photographs documenting rotundiform PV. Five were excluded owing to uncertain diagnosis, unclear clinical descriptions, or diagnoses unsubstantiated by examination under Wood's light or skin scrapings for potassium hydroxide examination. 13 had definite diagnosis of rotundiform PV. Ten agreed to attend clinic. The response rate was 76.9%. Ten age-and-sex pair-matched control subjects with non-rotundiform PV were recruited. Nine patients with rotundiform PV and two controls with non-rotundiform PV had their episode of PV representing their first episode of PV (p = 0.01; OR = 36.0, 95% CI: 2.2 - 866.9). We conclude that rotundiform PV is significantly associated with the first episode of PV. This phenomenon might be analogous to the herald patch being the primary lesion in pityriasis rosea.
我们报告一项回顾性病例对照研究，以调查花斑糠疹（PV）的圆形变体是否与PV的首发显著相关。我们的研究场景是由一位皮肤科顾问医生管理的皮肤科诊所。我们检索了2002年4月1日至2005年3月31日期间所有PV患者的病历。我们识别出皮损形成闭合圆圈的患者。我们排除了诊断不确定或经伍德灯检查或氢氧化钾检查的皮肤刮片未证实诊断的患者。对于每位患者，我们检索了下一位同性且年龄相近（±3岁）、有记录的非圆形PV且经检查证实诊断的患者的病历作为对照。在病历检索期间，80例患者被诊断为患有PV。18例有记录圆形PV的临床描述或临床照片。5例因诊断不确定、临床描述不清楚或经伍德灯下检查或氢氧化钾检查的皮肤刮片未证实诊断而被排除。13例被确诊为圆形PV。10例同意到诊所就诊。应答率为76.9%。招募了10例年龄和性别匹配的非圆形PV对照受试者。9例圆形PV患者和2例非圆形PV对照患者的PV发作是其首次PV发作（p = 0.01；OR = 36.0，95%CI：2.2 - 866.9）。我们得出结论，圆形PV与PV的首发显著相关。这种现象可能类似于玫瑰糠疹中母斑作为原发性皮损。
