晚期慢性阻塞性肺疾病患者骨质疏松症和骨质减少症的患病率
Prevalence of osteoporosis and osteopenia in advanced chronic obstructive pulmonary disease patients.
作者信息
Bhattacharyya Parthasarathi, Paul Rantu, Ghosh Malabika, Dey Ratna, Dey Rana, Barooah Nirjoo, Islam Saidul, Acharya Dipabali, Nag Saikat, Bardhan Sujan
机构信息
Department of Clinical Research, Institute of Pulmocare and Research, Kolkata, India.
出版信息
Lung India. 2011 Jul;28(3):184-6. doi: 10.4103/0970-2113.83974.
BACKGROUND
Reduction of bone mineral density (BMD) is a known and established phenomenon in chronic obstructive pulmonary disease (COPD). However, there have been no data regarding osteoporosis/osteopenia in COPD patients in India.
AIM
To look for the degree and frequency of osteoporosis/osteopenia in our OPD patients being diagnosed as COPD.
MATERIALS AND METHODS
Thirty-seven randomly selected patients with COPD were assessed for BMD with commercially available ultrasound bone densitometer (HOLOGIC SAHARA) in a pulmonary OPD. Some cofactors for reduced BMD were also noted.
RESULTS
Out of the 37 COPD (all belonging to the GOLD III/IV category) patients studied, the BMD was found to be normal in 10 (27%) patients, while 27 (73%) patients were found to have osteopenia/osteoporosis [19 (51.35%) and 8 (21.62%) patients having osteopenia and osteoporosis, respectively].
CONCLUSION
Frequency of osteoporosis and osteopenia was found to be very high (73%) in our population of advanced COPD. The data suggest a need for further in-depth study regarding the issue.
背景
骨矿物质密度（BMD）降低是慢性阻塞性肺疾病（COPD）中一种已知且已确定的现象。然而，在印度，尚无关于COPD患者骨质疏松症/骨质减少症的数据。
目的
研究我院门诊诊断为COPD患者的骨质疏松症/骨质减少症的程度和发生率。
材料与方法
在肺部门诊，使用商用超声骨密度仪（HOLOGIC SAHARA）对37例随机选取的COPD患者进行骨密度评估。还记录了一些导致骨密度降低的辅助因素。
结果
在研究的37例COPD患者（均属于GOLD III/IV级）中，10例（27%）患者骨密度正常，而27例（73%）患者存在骨质减少/骨质疏松[分别有19例（51.35%）和8例（21.62%）患者患有骨质减少和骨质疏松]。
结论
在我们的重度COPD患者群体中，骨质疏松症和骨质减少症的发生率非常高（73%）。这些数据表明有必要对该问题进行进一步深入研究。
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