Burke G, Stuart B, Crowley P, Scanaill S N, Drumm J
Coombe Lying-In Hospital, Dublin, Ireland.
BMJ. 1990 Apr 21;300(6731):1044-5. doi: 10.1136/bmj.300.6731.1044.
To determine whether intrauterine growth retardation associated with normal umbilical artery blood flow is a benign condition.
A prospective comparative study of growth retarded fetuses with normal and abnormal umbilical artery blood flow.
The fetal assessment clinic of a large maternity hospital in Ireland.
179 Women with singleton pregnancies in which the fetal abdominal circumference, measured by ultrasonography, was below the fifth centile for gestation.
Perinatal deaths, fetal distress requiring caesarean section, preterm delivery, cerebral irritation.
Of 124 fetuses with normal flow, all physically normal fetuses survived but one baby had cerebral irritation; there were six preterm deliveries and four caesarean sections for fetal distress. Among 55 women with abnormal flow there were two midtrimester abortions, three perinatal deaths, and one case of cerebral irritation in physically normal fetuses.
Intrauterine growth retardation associated with normal umbilical blood flow is a different entity from that associated with abnormal flow, normal flow being largely benign and abnormal flow carrying a serious risk of adverse outcome.
确定与正常脐动脉血流相关的宫内生长受限是否为良性情况。
对脐动脉血流正常和异常的生长受限胎儿进行前瞻性对照研究。
爱尔兰一家大型妇产医院的胎儿评估诊所。
179名单胎妊娠女性，其胎儿经超声测量腹围低于妊娠周数的第五百分位数。
围产期死亡、因胎儿窘迫需剖宫产、早产、脑激惹。
在124例血流正常的胎儿中，所有身体正常的胎儿均存活，但有1例婴儿出现脑激惹；有6例早产，4例因胎儿窘迫行剖宫产。在55例血流异常的女性中，有2例孕中期流产，3例围产期死亡，身体正常的胎儿中有1例出现脑激惹。
与正常脐血流相关的宫内生长受限与脐血流异常相关的宫内生长受限是不同的情况，正常血流大多为良性，异常血流则有严重不良结局风险。
