酶免疫测定法和乳胶凝集技术在诊断深静脉血栓形成中D-二聚体检测的应用。
The use of D-Dimer assay by enzyme immunoassay and latex agglutination techniques in the diagnosis of deep vein thrombosis.
作者信息
Chapman C S, Akhtar N, Campbell S, Miles K, O'Connor J, Mitchell V E
机构信息
Department of Haematology, Leicester Royal Infirmary.
出版信息
Clin Lab Haematol. 1990;12(1):37-42. doi: 10.1111/j.1365-2257.1990.tb01108.x.
The blood of 107 patients undergoing venography for suspected deep vein thrombosis (DVT) was tested for D-Dimers using enzyme immunoassay (EIA) and two latex agglutination techniques. D-Dimer levels by EIA were raised in 88% of patients with proven DVT. However, levels detected with the two agglutination tests were much less sensitive, being raised in only 43% patients with DVT. A more sensitive rapid screening test is needed to provide a useful non-invasive test for the exclusion of DVT.
对107例因疑似深静脉血栓形成（DVT）而接受静脉造影的患者的血液，采用酶免疫测定法（EIA）和两种乳胶凝集技术检测D - 二聚体。经证实患有DVT的患者中，88%的患者通过EIA检测出D - 二聚体水平升高。然而，两种凝集试验检测到的水平敏感性要低得多，只有43%的DVT患者水平升高。需要一种更敏感的快速筛查试验，以提供一种有用的非侵入性试验来排除DVT。
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