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关于通路相关手部缺血的治疗策略。

Treatment strategies for access-related hand ischemia.

机构信息

Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, University of Florida College of Medicine, Gainesville, FL 32610-0128, USA.

出版信息

Semin Vasc Surg. 2011 Jun;24(2):128-36. doi: 10.1053/j.semvascsurg.2011.05.012.

Abstract

Access-related hand ischemia, commonly known as "steal syndrome," is one of the most challenging and worrisome complications for the access surgeon. The construction of an arteriovenous access results in a predictable decrease in the perfusion pressure distal to the anastomosis, which can result in ischemia if the compensatory mechanisms are inadequate. Several preoperative clinical features have been shown to identify patients at risk. The diagnosis of access-related hand ischemia is largely a clinical one that can be aided in equivocal cases with noninvasive vascular laboratory studies. The treatment goals are to reverse the hand ischemia and to preserve the access. There are a variety of different remedial treatments, including access ligation, correction of the inflow lesion, limiting the flow through the access, proximalization of arterial inflow, revision using distal inflow, and distal revascularization with interval ligation. The optimal choice is predicated on the timing and severity of symptoms in conjunction with the access type, its anticipated durability, patient comorbidities, distribution of occlusive disease, and availability of venous conduit. The distal revascularization with interval ligation procedure has emerged as our optimal treatment and reverses the ischemic symptoms and salvages the access in approximately 90% of the cases. It is incumbent on all access surgeons to be familiar with the management of access-related hand ischemia. A review of the underlying pathophysiology and treatment options will be provided along with our current treatment algorithm.

摘要

与通路相关的手部缺血,通常被称为“窃血综合征”,是通路外科医生面临的最具挑战性和令人担忧的并发症之一。动静脉通路的建立会导致吻合口远端的灌注压可预测性下降,如果代偿机制不足,可能导致缺血。已经有几项术前临床特征被证明可以识别出处于危险中的患者。与通路相关的手部缺血的诊断主要是临床诊断,在不明确的情况下,可以通过无创血管实验室研究来辅助诊断。治疗目标是逆转手部缺血并保留通路。有各种不同的治疗方法,包括通路结扎、纠正流入病变、限制通过通路的流量、动脉流入近端化、使用远端流入进行修正,以及间隔结扎进行远端再血管化。最佳选择取决于症状的时间和严重程度,同时还需要考虑通路类型、预期的耐久性、患者的合并症、阻塞性疾病的分布以及静脉导管的可用性。间隔结扎的远端再血管化手术已成为我们的最佳治疗方法,大约 90%的病例可以逆转缺血症状并挽救通路。所有通路外科医生都有责任熟悉与通路相关的手部缺血的管理。我们将提供基础病理生理学和治疗选择的回顾,以及我们当前的治疗算法。

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