Chebil A, Chaabani L, Kort F, Ben Youssef N, Turki F, El Matri L
Institut Hédi-Rais d'Ophtalmologie (Service B), boulevard 9-Avril, 1006 Bab Saadoun, Tunis, Tunisie.
J Fr Ophtalmol. 2012 Jan;35(1):30-4. doi: 10.1016/j.jfo.2011.02.019. Epub 2011 Sep 1.
To analyze the patterns of pediatric uveitis.
A retrospective study of 49 children with uveitis, examined from January 2000 to December 2009. All patients underwent a complete ophthalmic examination and an etiological search; follow-up varied from six months to seven years.
The mean age at onset of uveitis was 11.6 years (range, 5-14 years). The sex ratio was 1.04. Uveitis was bilateral in 59.20% of the patients, anterior in 22 cases (44.9%), intermediate in seven cases (14.3%), posterior in four cases (8.1%), and panuveitis was found in 16 cases (32.7%). In 57.2% of the patients, uveitis was idiopathic. Infectious uveitis was responsible for 14.1% of the cases, the most common of which were toxoplasmosis and toxocarosis. Systemic associations were found in 22.5%, with juvenile idiopathic arthritis in 6.2%. A specific ocular entity was responsible for 6.2% of the cases. Ocular complications occurred in 65.3% of the affected eyes, the most common being cataract (24.5%) and cystoid macular edema (20.5%). The final visual acuity was less than 20/200 in 18%.
Pediatric uveitis is rare but may cause visual loss. In our study, the cause of uveitis in childhood remains most often undiagnosed. Toxoplasmosis and toxocarosis are the most frequent infectious causes. Cataract was the most frequent complication. A strict ophthalmological follow-up is mandatory to improve the prognosis.
分析儿童葡萄膜炎的发病模式。
对2000年1月至2009年12月期间检查的49例葡萄膜炎患儿进行回顾性研究。所有患者均接受了全面的眼科检查和病因排查；随访时间从6个月至7年不等。
葡萄膜炎发病的平均年龄为11.6岁（范围5 - 14岁）。性别比为1.04。59.20%的患者葡萄膜炎为双侧性，22例（44.9%）为前部葡萄膜炎，7例（14.3%）为中间部葡萄膜炎，4例（8.1%）为后部葡萄膜炎，16例（32.7%）为全葡萄膜炎。57.2%的患者葡萄膜炎为特发性。感染性葡萄膜炎占病例的14.1%，其中最常见的是弓形虫病和弓蛔虫病。22.5%的患者存在全身关联疾病，其中幼年特发性关节炎占6.2%。6.2%的病例由特定眼部疾病引起。65.3%的患眼出现眼部并发症，最常见的是白内障（24.5%）和黄斑囊样水肿（20.5%）。最终视力低于20/200的患者占18%。
儿童葡萄膜炎虽罕见但可能导致视力丧失。在我们的研究中，儿童葡萄膜炎的病因大多仍未确诊。弓形虫病和弓蛔虫病是最常见的感染性病因。白内障是最常见的并发症。严格的眼科随访对于改善预后至关重要。
