儿童葡萄膜炎：一项意大利的临床与流行病学研究。

Uveitis in childhood: an Italian clinical and epidemiological study.

作者信息

Paroli Maria Pia, Spinucci Giovanni, Liverani Marco, Monte Rita, Pezzi Paolo Pivetti

机构信息

Department of Ophthalmology, Ocular Immunovirology Service, Sapienza University of Rome, Rome, Italy.

出版信息

Ocul Immunol Inflamm. 2009 Jul-Aug;17(4):238-42. doi: 10.1080/09273940802702561.

DOI:10.1080/09273940802702561

PMID:19657976

Abstract

PURPOSE

To investigate demographics, causes, features, and visual outcomes of pediatric uveitis.

METHODS

Retrospective cohort study including 257 patients younger than 16 years.

RESULTS

Mean age at onset of uveitis was 8.54 +/- 3.98 years; 54.5% of the patients were girls. Anterior uveitis occurred in 47.8%, intermediate in 19.4%, posterior in 24.9%, panuveitis in 7.8%. Ocular involvement was bilateral in 67.8%. Infectious uveitis represented 31% of all cases. Causes of severe visual loss were cataract, macular scars, macular edema/maculopathy, and secondary glaucoma. At follow-up 79.3% of eyes maintained a visual acuity between 20/32 and 20/20.

CONCLUSIONS

Uveitis is rarer in children than in adults. Patients with anterior uveitis comprised the largest group. Posterior uveitis in the pediatric population has a lower incidence than some decades ago. Visual prognosis of pediatric uveitis is improving, owing to an earlier diagnosis and a correct treatment.

摘要

目的

研究儿童葡萄膜炎的人口统计学特征、病因、特点及视力预后。

方法

回顾性队列研究，纳入257例16岁以下患者。

结果

葡萄膜炎发病的平均年龄为8.54±3.98岁；54.5%的患者为女性。前葡萄膜炎占47.8%，中间葡萄膜炎占19.4%，后葡萄膜炎占24.9%，全葡萄膜炎占7.8%。67.8%的患者双眼受累。感染性葡萄膜炎占所有病例的31%。导致严重视力丧失的原因有白内障、黄斑瘢痕、黄斑水肿/黄斑病变及继发性青光眼。随访时，79.3%的患眼视力维持在20/32至20/20之间。