Department of Internal Medicine, School of Medicine, Federal University of Ceará,Fortaleza, Ceará, Brazil.
Clin Infect Dis. 2011 Oct;53(7):693-5. doi: 10.1093/cid/cir496.
We report for the first time the successful use of fluconazole to treat cutaneous leishmaniasis due to Leishmania braziliensis. We used escalating doses from 5 to 8 mg/kg per day. At a dose of 5 mg/kg per day, 75% patients were cured, and at 8 mg/kg per day, the cure rate was 100%. Fluconazole was well tolerated.
我们首次报告了氟康唑成功治疗巴西利什曼原虫引起的皮肤利什曼病。我们使用了 5 至 8 毫克/公斤/天的递增剂量。每天 5 毫克/公斤的剂量，75%的患者治愈，每天 8 毫克/公斤的剂量，治愈率为 100%。氟康唑耐受性良好。
