Molino Annamaria, Giovannini Monica, Micciolo Rocco, Auriemma Alessandra, Fiorio Elena, Santo Antonio, Cetto Gian Luigi
Department of Medical Oncology, University of Verona, Verona, Italy.
Clin Med Oncol. 2008;2:487-90. Epub 2008 Sep 4.
In 125 early breast cancer patients who underwent multiple bone marrow aspirates, there was no significant difference in terms of disease-free and overall survival after a median follow-up of 163 months between the patients with or without micrometastasis at the time of primary surgery. However, when the time-dependent evolution of the bone marrow aspirates was taken into account, some evidence for a longer disease-free and overall survival was found for the patients with negative bone marrow.
在125例接受多次骨髓穿刺的早期乳腺癌患者中，在对主要手术时有无微转移的患者进行了163个月的中位随访后，其无病生存期和总生存期并无显著差异。然而，当考虑骨髓穿刺的时间依赖性演变时，发现骨髓阴性的患者有更长无病生存期和总生存期的一些证据。
