Simionescu Cristiana, Mărgăritescu Cl, Stepan A, Ciurea Raluca, Cernea N
Department of Pathology, University of Medicine and Pharmacy of Craiova, Romania.
Rom J Morphol Embryol. 2011;52(3):743-58.
Pseudotumoral uterine lesions include benign reactive and artefactual changes, epithelial and mesenchymal, which occasionally are incorrectly interpreted as malignant or even premalignant lesions. Although some of these changes may have architectural or cytological abnormality, they are different from those observed in premalignant and malignant uterine lesions. The most common pseudotumoral lesions of the endometrium include various types of epithelial and stromal metaplasia, pseudolymphomas, inflammatory pseudotumor, adenomyosis, post-therapy surgical changes, artefactual changes, etc. Most of these changes may coexist with endometrial hyperplasia or endometrial carcinoma, and also with some benign conditions such as polyps or in combination with hormonal therapy or even in normal cyclic endometrium. These associated endometrial changes may raise important issues regarding the diagnosis and subsequent therapy.
假性肿瘤性子宫病变包括良性反应性和人为性改变，涉及上皮和间充质，这些病变偶尔会被错误地解释为恶性甚至癌前病变。尽管其中一些改变可能存在结构或细胞学异常，但它们与子宫癌前病变和恶性病变中观察到的情况不同。子宫内膜最常见的假性肿瘤性病变包括各种类型的上皮和间质化生、假性淋巴瘤、炎性假瘤、子宫腺肌病、治疗后手术改变、人为性改变等。这些改变大多可与子宫内膜增生或子宫内膜癌同时存在，也可与一些良性情况如息肉并存，或与激素治疗相关，甚至在正常周期性子宫内膜中出现。这些相关的子宫内膜改变可能会引发关于诊断及后续治疗的重要问题。
