Pavia Sesma C, Caravaca Ribera M A, Valls Tolosa C, Albarrán Deogracias J M, Gallart Marsillas M, Vilaplana Duran R
Sección de Endocrinologia, Hospital Infantil, San Juan de Dios, Barcelona.
An Esp Pediatr. 1990 Mar;32(3):228-32.
Fifty one patients were diagnosed as having chronic lymphocytic thyroiditis, according the Fisher's criteria. Their ages range was between 4.2 to 17.8 years. According to their basal values of T4 and TSH, they were divided into the following groups: 1. Euthyroids (n = 14), with both thyroxine and thyrotrophin, within normal limits. 2. Hypothyroid group (n = 37), subdivided into: 2.a normal T4 and elevated TSH (n = 18); 2.b low T4 with high TSH (n = 19). The TRH test showed an exaggerated TSH response in four cases in the euthyroid group, and in all the cases of hypothyroid group. This test carried out at the time of diagnosis, can show up alterations in thyroid function, which are not detected by basal assessments of T4 and TSH. The most frequent isotope scan image, was that of a unilateral decreased uptake in one lobe. We consider it to be of graf interest, given that the fine biopsies performed in this area were all positive.
根据费舍尔标准，51例患者被诊断为慢性淋巴细胞性甲状腺炎。他们的年龄范围在4.2岁至17.8岁之间。根据他们的T4和TSH基础值，将他们分为以下几组：1.甲状腺功能正常组（n = 14），甲状腺素和促甲状腺素均在正常范围内。2.甲状腺功能减退组（n = 37），再细分为：2.a T4正常且TSH升高（n = 18）；2.b T4低且TSH高（n = 19）。TRH试验显示，甲状腺功能正常组有4例以及甲状腺功能减退组所有病例的TSH反应均过度。在诊断时进行此项试验，可显示甲状腺功能的改变，而这些改变通过T4和TSH的基础评估无法检测到。最常见的同位素扫描图像是一叶摄取减少的单侧图像。鉴于在该区域进行的精细活检均为阳性，我们认为这具有重要意义。
